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EEG with occipital slowing

MedGen UID:: 869047
•Concept ID:: C4023465
•: Finding

HPO:	HP:0011210

Definition

Slowing in occipital areas of the scalp EEG. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVEEG with occipital slowing

Abnormal nervous system physiology
- Abnormal nervous system electrophysiology
  - Abnormality of central nervous system electrophysiology
    - EEG abnormality
      - EEG with abnormally slow frequencies
        EEG with focal slow activity
        EEG with occipital slowing

Conditions with this feature

Intellectual disability, autosomal dominant 42

MedGen UID:: 934741
•Concept ID:: C4310774
•: Mental or Behavioral Dysfunction

GNB1 encephalopathy (GNB1-E) is characterized by moderate-to-severe developmental delay / intellectual disability, structural brain abnormalities, and often infantile hypotonia and seizures. Other less common findings include dystonia, reduced vision, behavior issues, growth delay, gastrointestinal (GI) problems, genitourinary (GU) abnormalities in males, and cutaneous mastocytosis.

See: Condition Record

Intellectual disability, autosomal dominant 42

Professional guidelines

PubMed

Quantitative EEG in the Differential Diagnosis of Dementia Subtypes.

Olğun Y, Aksoy Poyraz C, Bozluolçay M, Poyraz BÇ
J Geriatr Psychiatry Neurol 2024 Sep;37(5):368-378. Epub 2024 Jan 13 doi: 10.1177/08919887241227410. PMID: 38217438

Added Value of QEEG for the Differential Diagnosis of Common Forms of Dementia.

Livinț Popa L, Dragoș HM, Strilciuc Ș, Pantelemon C, Mureșanu I, Dina C, Văcăraș V, Mureșanu D
Clin EEG Neurosci 2021 May;52(3):201-210. Epub 2020 Nov 8 doi: 10.1177/1550059420971122. PMID: 33166175

Analysis of EEG patterns and genotypes in patients with Angelman syndrome.

Vendrame M, Loddenkemper T, Zarowski M, Gregas M, Shuhaiber H, Sarco DP, Morales A, Nespeca M, Sharpe C, Haas K, Barnes G, Glaze D, Kothare SV
Epilepsy Behav 2012 Mar;23(3):261-5. Epub 2012 Feb 16 doi: 10.1016/j.yebeh.2011.11.027. PMID: 22341959

See all (5)

Recent clinical studies

Etiology

Electroencephalographic slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment.

Lam AKF, Carrick J, Kao CH, Phillips CL, Zheng YZ, Yee BJ, Kim JW, Grunstein RR, Naismith SL, D'Rozario AL
Sleep 2024 Jun 13;47(6) doi: 10.1093/sleep/zsae051. PMID: 38394454 Free PMC Article

Longitudinal resting-state EEG in amyloid-positive patients along the Alzheimer's disease continuum: considerations for clinical trials.

Scheijbeler EP, de Haan W, Stam CJ, Twisk JWR, Gouw AA
Alzheimers Res Ther 2023 Oct 19;15(1):182. doi: 10.1186/s13195-023-01327-1. PMID: 37858173 Free PMC Article

Comparison of resting-state EEG between adults with Down syndrome and typically developing controls.

Hamburg S, Bush D, Strydom A, Startin CM
J Neurodev Disord 2021 Oct 14;13(1):48. doi: 10.1186/s11689-021-09392-z. PMID: 34649497 Free PMC Article

Resting-state electroencephalographic biomarkers of Alzheimer's disease.

Cecchetti G, Agosta F, Basaia S, Cividini C, Cursi M, Santangelo R, Caso F, Minicucci F, Magnani G, Filippi M
Neuroimage Clin 2021;31:102711. Epub 2021 May 29 doi: 10.1016/j.nicl.2021.102711. PMID: 34098525 Free PMC Article

Alpha rhythm slowing during initiation of carbamazepine therapy: implications for future cognitive performance.

Frost JD Jr, Hrachovy RA, Glaze DG, Rettig GM
J Clin Neurophysiol 1995 Jan;12(1):57-63. PMID: 7896910

See all (76)

Diagnosis

Resting-state electroencephalographic biomarkers of Alzheimer's disease.

Generalized and Lateralized Rhythmic Patterns.

Schmitt SE
J Clin Neurophysiol 2018 May;35(3):218-228. doi: 10.1097/WNP.0000000000000446. PMID: 29718831

Occipital lobe seizures and epilepsies.

Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

EEG in delirium.

Jacobson S, Jerrier H
Semin Clin Neuropsychiatry 2000 Apr;5(2):86-92. doi: 10.153/SCNP00500086. PMID: 10837097

Acute confusional migraine: variant of transient global amnesia.

Sheth RD, Riggs JE, Bodensteiner JB
Pediatr Neurol 1995 Feb;12(2):129-31. doi: 10.1016/0887-8994(94)00154-t. PMID: 7779209

See all (80)

Therapy

Longitudinal resting-state EEG in amyloid-positive patients along the Alzheimer's disease continuum: considerations for clinical trials.

Scheijbeler EP, de Haan W, Stam CJ, Twisk JWR, Gouw AA
Alzheimers Res Ther 2023 Oct 19;15(1):182. doi: 10.1186/s13195-023-01327-1. PMID: 37858173 Free PMC Article

A Near-Global Slowing of Background Activity and Epileptic Discharges in Children With Mild to Moderately Symptomatic COVID-19 Infection: An Electro-Neurophysiological Study.

Yılmaz A, Yayıcı Köken Ö, Şekeroğlu B, Şanlıdağ B
Clin EEG Neurosci 2022 Nov;53(6):532-542. Epub 2022 Mar 23 doi: 10.1177/15500594221088744. PMID: 35317638 Free PMC Article

Static Magnetic Field Stimulation over the Visual Cortex Increases Alpha Oscillations and Slows Visual Search in Humans.

Gonzalez-Rosa JJ, Soto-Leon V, Real P, Carrasco-Lopez C, Foffani G, Strange BA, Oliviero A
J Neurosci 2015 Jun 17;35(24):9182-93. doi: 10.1523/JNEUROSCI.4232-14.2015. PMID: 26085640 Free PMC Article

Occipital lobe seizures and epilepsies.

Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

Disulfiram-induced acute organic brain syndrome.

Kump JG, Flaten PA, Greenlaw CW
South Med J 1979 Aug;72(8):1023-4. doi: 10.1097/00007611-197908000-00042. PMID: 472804

See all (33)

Prognosis

Electroencephalographic slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment.

Lam AKF, Carrick J, Kao CH, Phillips CL, Zheng YZ, Yee BJ, Kim JW, Grunstein RR, Naismith SL, D'Rozario AL
Sleep 2024 Jun 13;47(6) doi: 10.1093/sleep/zsae051. PMID: 38394454 Free PMC Article

How does Arabic orthographic connectivity modulate brain activity during visual word recognition: an ERP study.

Taha H, Ibrahim R, Khateb A
Brain Topogr 2013 Apr;26(2):292-302. Epub 2012 Aug 3 doi: 10.1007/s10548-012-0241-2. PMID: 22864655

Occipital lobe seizures and epilepsies.

Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

Analysis of EEG patterns and genotypes in patients with Angelman syndrome.

Topographic mapping of EEG during sleep.

Zeitlhofer J, Anderer P, Obergottsberger S, Schimicek P, Lurger S, Marschnigg E, Saletu B, Deecke L
Brain Topogr 1993 Winter;6(2):123-9. doi: 10.1007/BF01191077. PMID: 8123427

See all (48)

Clinical prediction guides

Electroencephalographic slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment.

Lam AKF, Carrick J, Kao CH, Phillips CL, Zheng YZ, Yee BJ, Kim JW, Grunstein RR, Naismith SL, D'Rozario AL
Sleep 2024 Jun 13;47(6) doi: 10.1093/sleep/zsae051. PMID: 38394454 Free PMC Article

Inhibition of return in time-lapse: Brain Rhythms during grip force control for spatial attention.

Zappasodi F, Croce P, Di Matteo R, Brunetti M
Neuropsychologia 2021 Dec 10;163:108068. Epub 2021 Oct 20 doi: 10.1016/j.neuropsychologia.2021.108068. PMID: 34687747

How does Arabic orthographic connectivity modulate brain activity during visual word recognition: an ERP study.

Taha H, Ibrahim R, Khateb A
Brain Topogr 2013 Apr;26(2):292-302. Epub 2012 Aug 3 doi: 10.1007/s10548-012-0241-2. PMID: 22864655

Occipital lobe seizures and epilepsies.

Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

Alpha rhythm slowing during initiation of carbamazepine therapy: implications for future cognitive performance.

Frost JD Jr, Hrachovy RA, Glaze DG, Rettig GM
J Clin Neurophysiol 1995 Jan;12(1):57-63. PMID: 7896910

See all (77)